1900:
First isolation of adrenaline by Dr. Jokichi Takamine, the first president of Sankyo Shoten
1973:
Discovery of the first HMG-CoA reductase inhibitor by Sankyo - origin of the statin class
1985:
Daiichi discovers levofloxacin, the first third-generation quinolone
2002:
Launch of olmesartan, an angiotensin II receptor blocker
2015:
Launch of edoxaban, a non-vitamin K antagonist oral anticoagulant (NOAC) and direct factor Xa inhibitor
2020:
European Commission approval and first launch of bempedoic acid in Europe. Bempedoic acid and its fixed-dose combination with ezetimibe is approved for use in adults with primary hypercholesterolaemia or mixed dyslipidaemia in Europe**
References
**Bempedoic acid / the combination of bempedoic acid with ezetimibe was approved by the EMA in April 2020 with a first market launch in late 2020.